A Brief Pause (In case you missed it last week)
I’ve really enjoyed writing this newsletter and am grateful to everyone who has followed along. I’m taking a brief pause so I can give it the time and effort needed to make it genuinely worthwhile, with the goal of returning to the full newsletter this fall.
In the meantime, we’ll continue sharing curated quick links and research updates to help you stay abreast of the topics we cover. Thanks, as always, for reading.
Research Quick Links
The Use of a Handheld Non-Invasive Vagal Nerve Stimulation (nVNS) Device for the Treatment of Long COVID: A Pilot Randomized Controlled Trial | Journal of Primary and Community Health
Alternative Headline: Vagus nerve stimulator device shows improvements in fatigue for Long COVID patients
ADDRESS-LC: study protocol for a phase 2, triple-blind, randomised, placebo-controlled trial to evaluate the efficacy and safety of bezisterim (NE3107) in adults with long COVID | BMJ Open
Alternative Headline: Study will evaluate bezisterim, a drug that inhibits TLR (toll-like receptor)-driven neuroinflammation
Loss of vesicular monoamine transporter 2 in striatum of long COVID and relationship to neuropsychiatric symptoms | The Lancet eBio Medicine
Alternative headline: Study finds damaged neurons in LC patients, potentially leading to new approaches to treatment
Mapping 2-Year Psychiatric and Neurologic Risks After Infections Across Body Systems and Age Groups | Infectious Diseases | JAMA Psychiatry
Alternative Headline: Study shows different types of infections increase the risk for neurologic and psychiatric issues
Neurologic Manifestations of Long COVID Affect Adult Females More Severely Than Males | Annals of Clnical and Translational Neurology
Alternative Headline: Females with Long COVID have higher symptom burden, worse quality of life, and poorer cognitive function than males
SARS-CoV-2 and Cancer Biology: Exploring the Mechanistic Links | Cancer Reports
Alternative Headline: Evidence shows mechanisms of SARS-CoV-2–induced inflammatory stress responses and pathways involved in cancer progression
A Research Classification for Long COVID: Symptom Frequency and Severity Improve Accuracy of Machine Learning Models | Chronic Diseases and Translational Medicine
Alternative Headline: Machine learning models using symptom frequency and severity more accurately distinguish Long COVID cases than models relying solely on binary symptom presence
Perioperative outcomes in patients with myalgic encephalomyelitis/chronic fatigue syndrome undergoing general anesthesia: a retrospective matched-pair study | BMC Anesthesiology | Springer Nature Link
Alternative Headline: Postoperative pain scores and requirements for opioids higher in an ME/CFS patient group following general anesthesia
COVID-19 vaccination timing, relative to acute COVID-19, and subsequent risk of long COVID | The Lancet eBioMedicine
Alternative Headline: COVID-19 vaccination appears protective against Long COVID
Item comprehension and content coverage of patient-reported outcome measures for long COVID: a qualitative study | Quality of Life Research | Springer Nature Link
Alternative Headline: Patient-reported outcome measures evaluated by Long COVID patients for use in clinical trial
Battling the Bots and Defending Against Fraudulent Responses in an International Community-Engaged Web-Based Survey With People Living With Long COVID: Methodological Study | Journal of Medical Internet Research
Alternative Headline: Fraudulent responses to online survey research and recommendations for web-based survey research